Impact in Surgery

References and Clinical Studies

Supportive Clinical Outcome Studies with IMPACT®: Surgical Patients
  1. Farreras N et al. Effect of Early Postoperative Enteral Immunonutrition on Wound Healing in Patients Undergoing Surgery for Gastric Cancer. Clinical Nutrition. 2005;24:55-65.
  2. Braga M, Gianotti L, Vignali A, Di Carlo V. Preoperative Oral Arginine and n-3 Fatty Acid Supplementation Improves the Immunometabolic Host Response and Outcome after Colorectal Resection for Cancer. Surgery. 2002; 132:805-814.
  3. Gianotti L, Braga M, Nespoli L, Radaelli G, Beneduce A, Di Carlo V. A Randomized Controlled Trial of Preoperative Oral Supplementation with a Specialized Diet in Patients with Gastrointestinal Cancer. Gastroenterology. 2002; 122:1763-1770.
  4. Braga M, Gianotti L, Nespoli L, Radaelli G, Di Carlo V. Nutritional Approach in Malnourished Surgical Patients: A Prospective Randomized Study. Arch Surg.2002; 137:174-180.
  5. Tepaske R, Velthuis H, Oudemans-van Straaten HM, Heisterkamp, SH, van Deventer SJ, Ince C, et al. Effect of Preoperative Oral Immune-enhancing Nutritional Supplement on Patients at High Risk of Infection after Cardiac Surgery: A Randomised Placebo-controlled Trial. Lancet. 2001;358:696-701.
  6. Braga M et al. Artificial Nutrition after Major Pancreatic Resection. Results of a Prospective Randomized Clinical Trial. Journal of Parenteral and Enteral Nutrition 1999;23 (1):S2.
  7. Braga M et al. Perioperative Immunonutrition in Patients Undergoing Cancer Surgery: Results of a Randomized Double-blind Phase 3 Trial. Arch Surg. 1999;134:428-433.
  8. Snyderman CH et al. Reduced Postoperative Infections with an Immune-Enhancing Nutritional Supplement. The Laryngoscope. 1999; 109:915-921.
  9. Senkal M et al. Outcome and Cost-effectiveness of Perioperative Enteral Immunonutrition in Patients Undergoing Elective Upper Gastrointestinal Tract Surgery: A Prospective Randomized Study. Arch Surg 1999;134:1309-1316.
  10. Braga M, Gianotti L, Vignali A, Cestari A, Bisagni P, Di Carlo V. Artificial Nutrition after Major Abdominal Surgery: Impact® of Route of Administration and Composition of the Diet. Crit Care Med. 1998;26:24-30.
  11. Senkal M, Mumme A, Eickhoff U, Geier B, Spath G, Wulfert D, et al. Early Postoperative Enteral Immunonutrition: Clinical Outcome and Cost-Comparison Analysis in Surgical Patients. Crit Care Med. 1997;25:1489-1496.
  12. Gianotti L, Braga M, Vignali A, Balzano G, Zerbi A, Bisagni P, et al. Effect of Route of Delivery and Formulation of Postoperative Nutritional Support in Patients Undergoing Major Operations for Malignant Neoplasms. Arch Surg. 1997;132:1222-1230.
  13. Schilling J, Vranjes N, Fierz W, Joller H, Gyurech D, Ludwig E, et al. Clinical outcome and immunology of postoperative arginine, omega-3 fatty acids and nucleotide-enriched enteral feeding: A randomized prospective comparison with standard enteral and low calorie/low fat IV solutions. Nutrition. 1996;12:423-429.
  14. Daly JM, Weintraub FN, Shou J, Rosato EF, Lucia M. Enteral Nutrition during Multimodality Therapy in Upper Gastrointestinal Cancer Patients. Ann Surg. 1995;221:327-338.
  15. Braga M, Vignali A, Gianotti L, Cestari A, Profili M, Di Carlo V. Benefits of Early Postoperative Enteral Feeding in Cancer Patients. Infusionsther Transfusionsmed 1995; 22:280-284.
  16. Daly JM et al. Enteral Nutrition with Supplemental Arginine, RNA, and Omega-3 Fatty Acids in Patients after Operation: Immunologic, Metabolic, and Clinical Outcome. Surgery. 1992;112:56-67.